In a longitudinal study, the dose–response relationships between long term occupational exposure to whole-body vibration and degenerative processes in the lumbar spine caused by the lumbar disks were examined. From 1990 to 1992, 388 vibration-exposed workers from different driving jobs were examined medically and by lumbar X-ray. For each individual, a history of all exposure conditions was recorded, and a cumulative vibration dose was calculated allowing comparisons between groups of low, middle, and high intensity of exposure. 310 subjects were selected for a follow-up four years later, of whom 90.6% (n=281) agreed to participate. In comparing the exposure groups, the results indicate that the limit value of a_zw(8h)=0.8 m/s² should be reviewed. The best fit between the lifelong vibration dose and the occurrence of a lumbar syndrome was obtained by applying a daily reference ofa_zw(8h)=0.6 m/s² as a limit value. The results became more distinct still when only those subjects were included in the statistical analysis who had had no lumbar symptoms up to the end of the first year of exposure. The prevalence of lumbar syndrome is 1.55 times higher in the highly exposed group when compared to the reference group with low exposure (CI_95%=1.24/1.95). Calculating the cumulative incidence of new cases of lumbar syndrome in the follow-up period yields a relative risk of RR_MH=1.37 (CI_95%=0.86/2.17) for the highly exposed group. It is concluded that the limit value for the calculation of an individual lifelong vibration dose should be based on a daily reference exposure of a_zw(8h)=0.6 m/s². With increasing dose it is more and more probable that cases of lumbar syndrome are caused by exposure to vibration.