The objectives of our study were:​ a) to evaluate the relative efficacy of antipersonnel mine protection offered by various de-mining footwear;​ b) to determine the in-situ forces and strains experienced by the lower extremity under blast conditions;​ c) to document the blast event, and d) medically evaluate the injury to the lower extremity that results from activation of a antipersonnel blast mine. Four fresh frozen full human cadavers were used, and four combinations of protective footwear were evaluated. The cadaver lower extremities were instrumented with a uniaxial load cell placed in the proximal tibia and strain gages applied to the distal femur. Each lower extremity was suspended with the boot heel placed directly over the landmine. High-speed video (13,500 frames per second) was used to capture the blast event and load and strain data were sampled 100 kHz and 50 kHz, respectively. Orthopaedic traumatologists examined the post blast lower extremities to assess the injuries, which ranged from an open, mangled lower extremity to a closed, minimally displaced fracture of the talus and calcaneal fracture. The results of this study suggest that practical mine protective measures may be feasible.